1. Colored paper. When was the last time you received a serious business letter on colored paper? I'm not talking ivory, beige or jellyfishbelly white either. This color could be pea soup but more it's more charitibly called shale. It's stupid to do this. Don't.
2. Telling me your novel is really about teaching people about something. This is a kiss of death as far as I'm concerned. Sales wise it's a non starter. People buy novels for the stories. If they learn something, it's cause you wrote a compelling story. I get so turned off by "this novel will help people understand the joys of Rabbitania" that I barely skim the pages. That means you have to have BLISTERING good writing to survive the slush. Give your writing a fighting chance. Don't saddle it with a teaching credential.
3. Right hand justified margins and page layout to make it "look like a book". I read books; I know what they look like. This isn't a book, it's sample pages. There is a universal industry standard for ragged right margins on manuscript pages.